By Lionel Fry
Atopic eczema is the commonest and chronic dermatological noticeable regularly perform. over the past few years, advances were made within the genetics of atopy usually, more recent remedies were brought for topical use, and new options recommended within the etiology. therefore, a brand new textual content on atopic eczema is either well timed and worthwhile. Written through one of many world's so much amazing dermatologists, An Atlas of Atopic Eczema presents complete assurance of this epidermis affliction, together with new details on calcineurin inhibitors and their healing techniques. generally illustrated in colour, the atlas explores subject matters resembling genetics, etiology, pathogenesis, diagnosis, scientific good points, differential analysis, relationships to different kinds of eczema, and therapy. the writer lifts the veil of misunderstanding and is helping physicians remain on best of the problem the elevated prevalence of eczemas current.
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Extra info for An Atlas of Atopic Eczema (Encyclopedia of Visual Medicine Series)
Approximately one-third of patients with atopic eczema will not develop either asthma or allergic rhinitis, while 10% will have all three disorders. These findings suggest both common and specific etiological factors for the development of these three atopic disorders. Urticaria and migraine Although migraine and urticaria are not considered to be part of the atopic state, there does appear to be an increased incidence in so-called atopic individuals. Migraine and urticaria may have specific external triggers, as do the classical atopic disorders.
Migraine and urticaria may have specific external triggers, as do the classical atopic disorders. However, the exact pathogenetic mechanisms have not been elucidated for migraine, urticaria and atopic disorders, and thus there is speculation whether there could be a common predisposing factor to these diseases. Atopic keratoconjunctivitis This is distinct from the ‘allergic’ conjunctivitis that occurs with rhinitis. In kerotoconjunctivitis, the eyelids are lichenified, crusted and scaly and the conjunctiva is hyperemic (Figure 80).
However, whether this is the cause is not proven. Neuropeptides may also be involved in the intense pruritus associated with atopic eczema. SUMMARY The definite etiological factor is genetic. Allergens, or in other words, foreign proteins, either dietary or aeroallergens, probably play a role and the other possible contributory factors include micro-organisms, pollution and the ‘hygiene hypothesis’ (Figure 12). Possible triggers (Figure 13) and helpful measures (Figure 14) are discussed in more detail in the chapter on ‘Management’.